{"product_id":"ara-290","title":"ARA-290","description":"\u003cp dir=\"auto\"\u003e\u003cstrong\u003eARA-290\u003c\/strong\u003e (also known as \u003cstrong\u003eCibinetide\u003c\/strong\u003e or \u003cstrong\u003ePH-BSP\u003c\/strong\u003e) is a \u003cstrong\u003esynthetic 11-amino-acid peptide\u003c\/strong\u003e derived from the helix B surface domain of \u003cstrong\u003eerythropoietin\u003c\/strong\u003e (\u003cstrong\u003eEPO\u003c\/strong\u003e). This research compound is engineered to selectively activate the \u003cstrong\u003einnate repair receptor\u003c\/strong\u003e (IRR, a heteromer of EPOR and β-common receptor\/CD131) while lacking hematopoietic (red blood cell-stimulating) activity. It has attracted significant scientific interest for its potent \u003cstrong\u003etissue-protective\u003c\/strong\u003e, \u003cstrong\u003eanti-inflammatory\u003c\/strong\u003e, and \u003cstrong\u003eneuroprotective\u003c\/strong\u003e effects. Preliminary and advanced preclinical studies indicate that ARA-290 may reduce inflammation, promote tissue repair, alleviate neuropathic pain, protect against ischemia-reperfusion injury, and improve metabolic and microvascular function. Researchers utilize ARA-290 in laboratory and animal models to investigate mechanisms of non-hematopoietic EPO signaling, cytoprotection, chronic inflammation, neuropathy, and regenerative medicine. As a research-grade compound, ARA-290 is intended exclusively for in vitro and animal studies. Scientists value its high selectivity, short sequence, and ability to mimic EPO’s tissue-protective benefits without erythropoietic side effects.\u003c\/p\u003e\n\u003ch3 dir=\"auto\"\u003eKey Research Applications\u003c\/h3\u003e\n\u003cul dir=\"auto\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuropathic Pain and Nerve Repair\u003c\/strong\u003e — Preclinical studies show ARA-290 produces long-lasting relief of mechanical allodynia and hyperalgesia in nerve injury models, while suppressing spinal microglia activation and neuroinflammation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTissue Protection and Ischemia-Reperfusion Injury\u003c\/strong\u003e — ARA-290 demonstrates strong cytoprotective effects in models of kidney, heart, liver, and brain ischemia-reperfusion, reducing organ damage, apoptosis, and inflammation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic and Diabetic Complications\u003c\/strong\u003e — Investigations highlight improvements in glycemic control, insulin sensitivity, and diabetic neuropathy in type 2 diabetes models, with benefits on microvascular function and wound healing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Inflammatory and Wound Healing\u003c\/strong\u003e — It accelerates dermal wound closure, reduces chronic inflammation, and modulates cytokine responses in models of injury and inflammatory diseases.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroader Regenerative Effects\u003c\/strong\u003e — Emerging research explores its potential in traumatic brain injury, cardiomyopathy, retinal degeneration, and other conditions involving tissue stress and repair.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Omni Peptides","offers":[{"title":"16 MG","offer_id":51002073514231,"sku":null,"price":400.0,"currency_code":"AED","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0918\/6777\/5223\/files\/ara-290-16mg.png?v=1786034528","url":"https:\/\/dubaipeptides.ae\/products\/ara-290","provider":"Dubai Peptides","version":"1.0","type":"link"}