{"product_id":"kisspeptin-10","title":"KissPeptin-10","description":"\u003cp\u003e\u003cspan\u003eCan raise LH\/FSH\/testosterone transiently; reproductive axis modulation\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eKisspeptin-10\u003c\/strong\u003e (also known as \u003cstrong\u003eKp-10\u003c\/strong\u003e or \u003cstrong\u003eMetastin (45-54)\u003c\/strong\u003e) is a \u003cstrong\u003esynthetic decapeptide\u003c\/strong\u003e corresponding to the C-terminal bioactive fragment (residues 45-54) of the KISS1 gene product, a key upstream regulator of the hypothalamic-pituitary-gonadal (HPG) axis. This research compound has attracted extensive scientific interest for its potent stimulation of gonadotropin-releasing hormone (\u003cstrong\u003eGnRH\u003c\/strong\u003e) secretion and its role in reproductive endocrinology. Preliminary and advanced preclinical studies indicate that Kisspeptin-10 may robustly increase luteinizing hormone (\u003cstrong\u003eLH\u003c\/strong\u003e) and follicle-stimulating hormone (\u003cstrong\u003eFSH\u003c\/strong\u003e) release, support gonadotropin pulsatility, and influence reproductive behaviors and fertility. Researchers utilize this peptide in laboratory and animal models to investigate mechanisms of puberty onset, HPG axis regulation, hypogonadism, and neuroendocrine signaling. As a research-grade compound, Kisspeptin-10 is intended exclusively for in vitro and animal studies. Scientists value its high potency as a GPR54 (KISS1R) agonist, short half-life, and utility in elucidating kisspeptin-mediated control of reproduction and related pathologies.\u003c\/p\u003e\n\u003ch3 dir=\"auto\"\u003eKey Research Applications\u003c\/h3\u003e\n\u003cul dir=\"auto\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypothalamic-Pituitary-Gonadal Axis Stimulation\u003c\/strong\u003e — Preclinical studies demonstrate that Kisspeptin-10 potently elicits dose-dependent increases in LH and FSH secretion via direct activation of GnRH neurons. It enhances LH pulse frequency and amplitude in various models, including rodents and non-human primates, highlighting its central role in gonadotropin regulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFertility and Reproductive Hormone Restoration\u003c\/strong\u003e — Investigations show Kisspeptin-10 restores gonadal function in models of hypogonadotropic hypogonadism, hyperprolactinemia, and hypothyroidism, improving testosterone levels, testicular morphology, and sperm quality. It has been explored for reversing infertility states and supporting ovulation induction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePuberty Onset and Sexual Maturation\u003c\/strong\u003e — Research indicates Kisspeptin-10 advances pubertal development in prepubertal models and modulates sexual dimorphism in hormone responses, with implications for studying delayed or precocious puberty and sex-specific reproductive timing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReproductive Behavior and Sexual Function\u003c\/strong\u003e — Studies reveal effects on sexual motivation, partner preference, and arousal pathways, including modulation of brain activity in sexual-processing networks and potential benefits in models of hypoactive sexual desire disorder (HSDD).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroader Metabolic and Endocrine Effects\u003c\/strong\u003e — Emerging preclinical data suggest influences on energy balance, metabolic regulation in obesity-diabetes models, and interactions with other neuroendocrine systems, including potential roles in insulin sensitivity and gonadal steroidogenesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 dir=\"auto\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul dir=\"auto\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e: C₆₃H₈₃N₁₇O₁₄\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e: 1302.4 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence\u003c\/strong\u003e: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ (C-terminal amidation)\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Omni Peptides","offers":[{"title":"10mg","offer_id":50413272989943,"sku":"KP10","price":250.0,"currency_code":"AED","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0918\/6777\/5223\/files\/kp-10mg_d1c9eda0-8681-492e-986b-8907f99fc9dd.png?v=1768027696","url":"https:\/\/dubaipeptides.ae\/products\/kisspeptin-10","provider":"Dubai Peptides","version":"1.0","type":"link"}