{"product_id":"mots-c","title":"MOTS-c","description":"\u003cp\u003e\u003cspan\u003eClean GH boost, recovery, fat metabolism\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eMOTS-c\u003c\/strong\u003e (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a \u003cstrong\u003esynthetic version\u003c\/strong\u003e of the naturally occurring 16-amino-acid \u003cstrong\u003emitochondrial-derived peptide\u003c\/strong\u003e (MDP) encoded by a short open reading frame within the mitochondrial 12S rRNA gene (MT-RNR1). This research compound has attracted significant scientific interest for its role as a \u003cstrong\u003emetabolic regulator\u003c\/strong\u003e and \u003cstrong\u003eexercise mimetic\u003c\/strong\u003e. Preliminary and advanced preclinical studies indicate that MOTS-c may activate AMP-activated protein kinase (AMPK), enhance glucose uptake in skeletal muscle, promote metabolic flexibility, reduce insulin resistance, and support mitochondrial biogenesis. Researchers utilize this peptide in laboratory and animal models to explore mechanisms of energy homeostasis, particularly in models of obesity, type 2 diabetes, aging, and exercise physiology. As a research-grade compound, MOTS-c is intended exclusively for in vitro and animal studies. Scientists value its unique mitochondrial origin, systemic hormonal-like actions, and potential to elucidate mitochondrial-nuclear communication in metabolic health.\u003c\/p\u003e\n\u003ch3 dir=\"auto\"\u003eKey Research Applications\u003c\/h3\u003e\n\u003cul dir=\"auto\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic Homeostasis and Insulin Sensitivity\u003c\/strong\u003e — Preclinical investigations show that MOTS-c improves insulin sensitivity, enhances glucose uptake in skeletal muscle via the folate-AICAR-AMPK pathway, and counters high-fat diet-induced insulin resistance and obesity in various models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExercise Mimetic Effects\u003c\/strong\u003e — MOTS-c is upregulated in response to exercise and mimics many of its benefits, including increased energy expenditure, improved physical performance, and metabolic adaptations in skeletal muscle, with enhanced endurance observed in aged and obese animal models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eObesity and Weight Management\u003c\/strong\u003e — Studies demonstrate that MOTS-c reduces body weight gain, promotes fat oxidation, and prevents diet-induced obesity through modulation of lipid metabolism and thermogenesis in adipose tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAging and Longevity Support\u003c\/strong\u003e — Research highlights its role in counteracting age-related metabolic decline, improving muscle function, and potentially extending healthspan by enhancing mitochondrial stress responses and reducing oxidative damage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroader Protective Effects\u003c\/strong\u003e — Investigations suggest benefits in bone metabolism regulation (promoting osteoblast activity and inhibiting osteoclastogenesis), liver health (reducing steatosis in NAFLD models), anti-inflammatory actions, and protection against metabolic stress in various organ systems.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 dir=\"auto\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul dir=\"auto\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e: C₁₀₁H₁₅₂N₂₈O₂₂S₂\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e: 2174.6 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence\u003c\/strong\u003e: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Omni Peptides","offers":[{"title":"10mg","offer_id":50413243433207,"sku":"MS10","price":300.0,"currency_code":"AED","in_stock":true},{"title":"40mg","offer_id":50413243465975,"sku":"MS40","price":980.0,"currency_code":"AED","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0918\/6777\/5223\/files\/motsc.png?v=1768028138","url":"https:\/\/dubaipeptides.ae\/products\/mots-c","provider":"Dubai Peptides","version":"1.0","type":"link"}