{"product_id":"n-acetyl-semax-amidate","title":"N-Acetyl Semax Amidate","description":"\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eN-Acetyl Semax Amidate\u003c\/strong\u003e (also known as \u003cstrong\u003eN-Acetyl Semax NH₂\u003c\/strong\u003e or \u003cstrong\u003eAc-Semax Amidate\u003c\/strong\u003e) is a \u003cstrong\u003esynthetic heptapeptide\u003c\/strong\u003e derived from Semax with two key stabilizing modifications: \u003cstrong\u003eN-terminal acetylation\u003c\/strong\u003e and \u003cstrong\u003eC-terminal amidation\u003c\/strong\u003e. These changes significantly improve enzymatic resistance (especially against aminopeptidases), enhance metabolic stability, and often improve blood-brain barrier penetration and duration of action compared to standard Semax.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003eThis research compound retains the core ACTH(4-10) analog sequence (Met-Glu-His-Phe-Pro-Gly-Pro) and is studied for its potent \u003cstrong\u003enootropic\u003c\/strong\u003e, \u003cstrong\u003eneuroprotective\u003c\/strong\u003e, \u003cstrong\u003eneurotrophic\u003c\/strong\u003e, and \u003cstrong\u003ecognitive-enhancing\u003c\/strong\u003e properties. Preclinical research suggests it strongly upregulates BDNF and TrkB expression, modulates dopaminergic and serotonergic systems, reduces oxidative stress and neuroinflammation, and supports neuroplasticity with potentially superior pharmacokinetics to unmodified Semax.\u003c\/p\u003e\n\u003ch3 dir=\"auto\"\u003eKey Research Applications\u003c\/h3\u003e\n\u003cul dir=\"auto\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eCognitive Enhancement \u0026amp; Nootropic Effects\u003c\/strong\u003e — Studied for improvements in memory, learning, attention, and mental performance under stress, fatigue, or aging conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroprotection\u003c\/strong\u003e — Investigated in models of cerebral ischemia, stroke recovery, traumatic brain injury, and neurodegeneration for its ability to reduce neuronal damage, apoptosis, and oxidative stress.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBDNF \u0026amp; Neurotrophic Support\u003c\/strong\u003e — Promotes BDNF expression and hippocampal neurogenesis, supporting long-term synaptic plasticity and cognitive resilience.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Inflammatory \u0026amp; Anti-Stress Action\u003c\/strong\u003e — Modulates neuroinflammation and helps normalize neurotransmitter balance during acute or chronic stress.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePeptide Optimization\u003c\/strong\u003e — The dual modification (N-acetylation + C-amidation) is commonly researched for better stability, longer half-life, and enhanced intranasal or systemic efficacy compared to native Semax.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 dir=\"auto\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul dir=\"auto\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e: C₃₉H₅₃N₉O₁₁S\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e: 855.96 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence\u003c\/strong\u003e: Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH₂ (N-terminal acetylation, C-terminal amidation)\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Omni Peptides","offers":[{"title":"10 mg","offer_id":50722502934775,"sku":null,"price":250.0,"currency_code":"AED","in_stock":true},{"title":"50 mg","offer_id":50832685302007,"sku":null,"price":1000.0,"currency_code":"AED","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0918\/6777\/5223\/files\/nasemax_10mg.png?v=1777542709","url":"https:\/\/dubaipeptides.ae\/products\/n-acetyl-semax-amidate","provider":"Dubai Peptides","version":"1.0","type":"link"}