Omni Peptides

PT-141

Dhs. 250.00 AED

Sale Sold out

VIAL

Freeze-dried powder in a sealed glass vial. Reconstitute with bacteriostatic water and administer via syringe. The most versatile and cost-effective research format.

RECONSTITUTION & SYRINGE REQUIRED

CARTRIDGE

Pre-filled and ready to administer. Slides into a reusable pen injector — no measuring or mixing required. Clean, discreet, and consistent across research protocols.

REQUIRES COMPATIBLE PEN INJECTOR

NASAL

Delivered via mucosal absorption — no needles required. A popular choice for research protocols where needle-free administration is preferred.

NEEDLE-FREE — SPRAY & GO

PEN

An all-in-one auto-injector with the cartridge pre-loaded. Dial, click, and administer. Optimal for high-frequency research protocols requiring precise, repeatable dosing.

DIAL, CLICK & INJECT — NO PREP

Vials are freeze-dried (lyophilised) powder — kept refrigerated unopened, they remain stable for up to 2 years.

Cartridges, nasal sprays, and pens arrive pre-filled as liquid, must be kept refrigerated at all times, and carry a Beyond Use Date — typically 4–8 weeks from receipt. Please refer to the BUD on the label.

Size 10mg

PT-141 (also known as Bremelanotide or PT141) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH). This research compound has attracted substantial scientific interest for its selective agonism at melanocortin receptors (primarily MC3R and MC4R), predominantly expressed in the central nervous system. Preliminary and advanced preclinical studies indicate that PT-141 may activate hypothalamic pathways to enhance sexual arousal and desire, induce penile erections in animal models, and modulate sexual behavior without direct reliance on vascular mechanisms. Researchers utilize this peptide in laboratory and animal models to investigate mechanisms of central sexual response, libido regulation, hypoactive sexual desire disorder (HSDD), and erectile dysfunction. As a research-grade compound, PT-141 is intended exclusively for in vitro and animal studies (note: bremelanotide has received regulatory approval for specific clinical indications such as HSDD in premenopausal women under the brand Vyleesi, but research formulations remain designated for laboratory use). Scientists value its unique CNS-targeted action, distinguishing it from PDE5 inhibitors, and its utility in elucidating melanocortin-mediated pathways in reproductive neuroendocrinology.

Molecular Formula

C₅₀H₆₈N₁₄O₁₀

Molecular Weight

1025.2 g/mol

Sequence

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (cyclic heptapeptide lactam; Nle = norleucine; D-Phe = D-phenylalanine; C-terminal carboxylic acid)

Research Applications

Sexual Arousal and Desire Enhancement
Preclinical investigations demonstrate that PT-141 potently activates melanocortin receptors in the hypothalamus, increasing sexual motivation, arousal, and desire in various animal models. It elicits dose-dependent penile erections in rats and nonhuman primates via central neural pathways, with activation confirmed by c-Fos expression in relevant brain regions.
Erectile Function Studies
Research shows PT-141 induces erectile responses in normal and erectile dysfunction models, often with synergistic effects when combined with PDE5 inhibitors like sildenafil. Studies explore its rapid onset and CNS-mediated mechanism as a potential alternative or adjunct for vascular-independent erectile support.
Hypoactive Sexual Desire Disorder (HSDD) Models
PT-141 is extensively studied for restoring sexual desire in models of low libido, including female HSDD. It modulates brain pathways involved in sexual response, offering insights into non-hormonal approaches to female sexual dysfunction.
Neuroendocrine and Behavioral Effects
Investigations highlight PT-141's influence on sexual behaviors, partner preference, and arousal networks in the brain. Research examines its specificity for melanocortin receptors without significant tanning effects (unlike related melanotan analogs) and its potential in broader reproductive behavior models.
Broader CNS and Physiological Implications
Emerging studies probe its roles in modulating other melanocortin-mediated functions, including potential interactions with appetite, stress, and reward pathways, with implications for understanding central regulation of sexual and motivational states.

Storage & Handling

Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.

Beyond Use Date

Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.