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Omni Peptides

Tesamorelin

Regular price Dhs. 500.00 AED
Regular price Sale price Dhs. 500.00 AED
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GHRH analog; strongest visceral/abdominal fat burner, clean GH/IGF-1 boost

Tesamorelin (also known as TH9507) is a synthetic 44-amino-acid polypeptide analog of human growth hormone-releasing hormone (GHRH), featuring an N-terminal modification with a trans-3-hexenoyl group for enhanced stability and resistance to enzymatic degradation. This research compound has garnered significant scientific interest for its ability to stimulate pulsatile endogenous growth hormone (GH) secretion from the anterior pituitary, thereby elevating insulin-like growth factor-1 (IGF-1) levels and influencing metabolic pathways. Preliminary and advanced preclinical studies indicate that tesamorelin may promote lipolysis, reduce visceral adipose tissue, support muscle preservation, and modulate body composition. Researchers employ this peptide in laboratory and animal models to investigate mechanisms of GH axis regulation, fat metabolism, and endocrine responses, particularly in models of metabolic dysregulation and age-related decline. As a research-grade compound, tesamorelin is intended exclusively for in vitro and animal studies. Scientists value its improved pharmacokinetic profile over native GHRH and its utility in elucidating targeted GH stimulation without direct exogenous hormone administration.

Molecular Formula
C₂₂₁H₃₆₆N₇₂O₆₇S
Molecular Weight
5135.9 g/mol (free base)
Sequence
trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂ (C-terminal amidation)
  • Visceral Adipose Tissue Reduction
    Preclinical and clinical-model studies demonstrate that tesamorelin significantly decreases visceral fat accumulation through enhanced lipolysis and triglyceride reduction. It has been extensively investigated in models of HIV-associated lipodystrophy and central obesity, showing preferential effects on abdominal fat while preserving subcutaneous adipose tissue.
  • Growth Hormone Axis Stimulation
    Tesamorelin potently activates GHRH receptors to induce pulsatile GH release and elevate IGF-1 levels. Research explores its role in restoring GH secretion in states of relative deficiency, including aging, metabolic syndrome, and antiretroviral therapy-related endocrine disruption.
  • Body Composition and Muscle Health
    Investigations reveal tesamorelin's potential to increase lean muscle area and density in truncal muscle groups, while improving muscle quality metrics (e.g., Hounsfield units) in models of sarcopenia and fat infiltration. Studies assess its anabolic effects alongside fat loss for better overall body composition.
  • Metabolic and Lipid Profile Modulation
    Tesamorelin favorably influences lipid metabolism, insulin sensitivity, and energy balance in preclinical models. Research examines its impact on triglycerides, liver fat, and metabolic parameters in obesity and diabetes-related contexts.
  • Broader Endocrine and Protective Effects
    Emerging studies probe its applications in neuroprotection, cardiovascular health, and age-related metabolic decline, with implications for investigating GH-mediated anabolic and lipolytic pathways across multiple organ systems.
Storage & Handling

Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.

Beyond Use Date

Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.