{"product_id":"tesamorelin","title":"Tesamorelin","description":"\u003cp\u003e\u003cspan\u003eGHRH analog; strongest visceral\/abdominal fat burner, clean GH\/IGF-1 boost\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eTesamorelin\u003c\/strong\u003e (also known as \u003cstrong\u003eTH9507\u003c\/strong\u003e) is a \u003cstrong\u003esynthetic 44-amino-acid polypeptide\u003c\/strong\u003e analog of human \u003cstrong\u003egrowth hormone-releasing hormone\u003c\/strong\u003e (\u003cstrong\u003eGHRH\u003c\/strong\u003e), featuring an N-terminal modification with a \u003cstrong\u003etrans-3-hexenoyl\u003c\/strong\u003e group for enhanced stability and resistance to enzymatic degradation. This research compound has garnered significant scientific interest for its ability to stimulate pulsatile endogenous \u003cstrong\u003egrowth hormone\u003c\/strong\u003e (\u003cstrong\u003eGH\u003c\/strong\u003e) secretion from the anterior pituitary, thereby elevating \u003cstrong\u003einsulin-like growth factor-1\u003c\/strong\u003e (\u003cstrong\u003eIGF-1\u003c\/strong\u003e) levels and influencing metabolic pathways. Preliminary and advanced preclinical studies indicate that tesamorelin may promote lipolysis, reduce visceral adipose tissue, support muscle preservation, and modulate body composition. Researchers employ this peptide in laboratory and animal models to investigate mechanisms of GH axis regulation, fat metabolism, and endocrine responses, particularly in models of metabolic dysregulation and age-related decline. As a research-grade compound, tesamorelin is intended exclusively for in vitro and animal studies. Scientists value its improved pharmacokinetic profile over native GHRH and its utility in elucidating targeted GH stimulation without direct exogenous hormone administration.\u003c\/p\u003e\n\u003ch3 dir=\"auto\"\u003eKey Research Applications\u003c\/h3\u003e\n\u003cul dir=\"auto\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eVisceral Adipose Tissue Reduction\u003c\/strong\u003e — Preclinical and clinical-model studies demonstrate that tesamorelin significantly decreases visceral fat accumulation through enhanced lipolysis and triglyceride reduction. It has been extensively investigated in models of HIV-associated lipodystrophy and central obesity, showing preferential effects on abdominal fat while preserving subcutaneous adipose tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth Hormone Axis Stimulation\u003c\/strong\u003e — Tesamorelin potently activates GHRH receptors to induce pulsatile GH release and elevate IGF-1 levels. Research explores its role in restoring GH secretion in states of relative deficiency, including aging, metabolic syndrome, and antiretroviral therapy-related endocrine disruption.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBody Composition and Muscle Health\u003c\/strong\u003e — Investigations reveal tesamorelin's potential to increase lean muscle area and density in truncal muscle groups, while improving muscle quality metrics (e.g., Hounsfield units) in models of sarcopenia and fat infiltration. Studies assess its anabolic effects alongside fat loss for better overall body composition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic and Lipid Profile Modulation\u003c\/strong\u003e — Tesamorelin favorably influences lipid metabolism, insulin sensitivity, and energy balance in preclinical models. Research examines its impact on triglycerides, liver fat, and metabolic parameters in obesity and diabetes-related contexts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroader Endocrine and Protective Effects\u003c\/strong\u003e — Emerging studies probe its applications in neuroprotection, cardiovascular health, and age-related metabolic decline, with implications for investigating GH-mediated anabolic and lipolytic pathways across multiple organ systems.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 dir=\"auto\"\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul dir=\"auto\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e: C₂₂₁H₃₆₆N₇₂O₆₇S\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e: 5135.9 g\/mol (free base)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence\u003c\/strong\u003e: trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂ (C-terminal amidation)\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Omni Peptides","offers":[{"title":"10mg","offer_id":50413275873527,"sku":"TSM10","price":500.0,"currency_code":"AED","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0918\/6777\/5223\/files\/ts-10mg.png?v=1768028138","url":"https:\/\/dubaipeptides.ae\/products\/tesamorelin","provider":"Dubai Peptides","version":"1.0","type":"link"}