Omni Peptides
5-Amino-1MQ
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5-Amino-1MQ (also written as 5A1MQ, 5-AM1Q, or 5-Amino-1-methylquinolinium) is a synthetic small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT). This research compound has generated significant scientific interest for its ability to modulate cellular NAD⁺ metabolism, energy homeostasis, and adipose/muscle tissue function by blocking NNMT-mediated methylation of nicotinamide. Preliminary and advanced preclinical studies indicate that 5-Amino-1MQ may elevate intracellular NAD⁺ levels, enhance sirtuin activity, promote fatty acid oxidation, support muscle regeneration, and improve metabolic parameters. Researchers utilize this compound in laboratory and animal models to investigate mechanisms of NNMT overexpression in obesity, insulin resistance, sarcopenia, and age-related metabolic decline. As a research-grade compound, 5-Amino-1MQ is intended exclusively for in vitro and animal studies. Scientists value its cell permeability, oral bioavailability in research models, high selectivity for NNMT, and utility in elucidating the role of the NNMT–NAD⁺ axis in metabolic and regenerative biology.
Research Applications
Storage & Handling
Storage & Handling
Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.
Beyond Use Date
Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.
— About this compound
5-Amino-1MQ is a selective NNMT-inhibiting small molecule.
5-Amino-1MQ (also written as 5A1MQ, 5-AM1Q, or 5-Amino-1-methylquinolinium) is a synthetic small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT). This research compound has generated significant scientific interest for its ability to modulate cellular NAD⁺ metabolism, energy homeostasis, and adipose/muscle tissue function by blocking NNMT-mediated methylation of nicotinamide. Preliminary and advanced preclinical studies indicate that 5-Amino-1MQ may elevate intracellular NAD⁺ levels, enhance sirtuin activity, promote fatty acid oxidation, support muscle regeneration, and improve metabolic parameters. Researchers utilize this compound in laboratory and animal models to investigate mechanisms of NNMT overexpression in obesity, insulin resistance, sarcopenia, and age-related metabolic decline. As a research-grade compound, 5-Amino-1MQ is intended exclusively for in vitro and animal studies. Scientists value its cell permeability, oral bioavailability in research models, high selectivity for NNMT, and utility in elucidating the role of the NNMT–NAD⁺ axis in metabolic and regenerative biology.
Research Applications
Where researchers apply it.
— Verified & Documented
Every vial is backed by a Certificate of Analysis.
Each lot is independently characterised by HPLC and mass spectrometry, with identity, mass and purity documented per batch and available on request.
Additional quality-control testing, including sterility, endotoxin and heavy metals, is conducted periodically across our product range.
Storage & Handling
Storage & Handling
Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.
Beyond Use Date
Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.