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Omni Peptides

GLP3 RT

Regular price Dhs. 700.00 AED
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Size
Quantity
Lyophilised & sealed vials
Independent COA · ≥99% purity
Cold-chain dispatch · same day Dubai
Discreet · unbranded outer packaging

GLP3 RT (also known as LY3437943) is a synthetic long-acting peptide engineered as a triple agonist of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). This research compound has generated substantial scientific interest for its potential in modulating energy metabolism, appetite regulation, and glucose homeostasis. Preliminary and advanced preclinical studies, along with emerging clinical data, indicate that this may induce significant weight reduction, improve glycemic control, enhance lipid profiles, and promote liver fat reduction through synergistic activation of these incretin and glucagon pathways. Researchers employ this peptide in laboratory and animal models to investigate mechanisms of obesity, type 2 diabetes, metabolic dysfunction-associated steatotic liver disease (MASLD), and related metabolic disorders. As a research-grade compound, this is intended exclusively for in vitro and animal studies. Scientists value its balanced potency profile across the three receptors and its utility in advancing understanding of multi-receptor agonism in metabolic regulation.

Molecular Formula
C₂₂₁H₃₄₂N₄₆O₆₈
Molecular Weight
4731.3 g/mol
Sequence
Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-(α-Me-Leu)-Leu-Asp-Lys-[side chain modified Lys]-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂
01 Obesity and Weight Management
Preclinical models demonstrate that this markedly reduces body weight through decreased food intake, delayed gastric emptying, and increased energy expenditure. Studies show superior efficacy compared to dual agonists, with substantial fat mass loss and preservation of lean mass in various obesity models.
02 Glycemic Control and Type 2 Diabetes
Enhances glucose-dependent insulin secretion, improves insulin sensitivity, and lowers fasting glucose and HbA1c levels in diabetic and prediabetic models. Its triple agonism supports better metabolic outcomes than single or dual incretin therapies.
03 Liver Health and MASLD/MASH
Investigations reveal potent reductions in liver fat content, improvements in steatosis, and modulation of fibrosis markers. Preclinical and early clinical data highlight its role in reversing metabolic dysfunction-associated steatotic liver disease through combined effects on lipid metabolism and inflammation.
04 Lipid Metabolism and Cardiovascular Support
Favorably alters lipid profiles by reducing triglycerides, LDL, and VLDL while promoting fat oxidation and ketone body production. Research explores its potential benefits in mitigating obesity-related cardiovascular risk factors.
05 Broader Metabolic and Oncologic Implications
Emerging studies suggest protective effects against obesity-associated cancer progression, with reduced tumor growth and immune reprogramming in preclinical tumor models, potentially linked to sustained weight loss and metabolic improvements.
Storage & Handling

Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.

Beyond Use Date

Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.

Molecular Formula
C₂₂₁H₃₄₂N₄₆O₆₈
Molecular Weight
4731.3 g/mol
Sequence
Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-(α-Me-Leu)-Leu-Asp-Lys-[side chain modified Lys]-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂

— About this compound

GLP3 RT is a synthetic GLP-3 receptor agonist peptide.

GLP3 RT (also known as LY3437943) is a synthetic long-acting peptide engineered as a triple agonist of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). This research compound has generated substantial scientific interest for its potential in modulating energy metabolism, appetite regulation, and glucose homeostasis. Preliminary and advanced preclinical studies, along with emerging clinical data, indicate that this may induce significant weight reduction, improve glycemic control, enhance lipid profiles, and promote liver fat reduction through synergistic activation of these incretin and glucagon pathways. Researchers employ this peptide in laboratory and animal models to investigate mechanisms of obesity, type 2 diabetes, metabolic dysfunction-associated steatotic liver disease (MASLD), and related metabolic disorders. As a research-grade compound, this is intended exclusively for in vitro and animal studies. Scientists value its balanced potency profile across the three receptors and its utility in advancing understanding of multi-receptor agonism in metabolic regulation.

VIAL ANATOMY
LYOPHILISED VIAL
Flip-off cap
Tamper-evident seal
Rubber stopper
Bacteriostatic-water compatible
Batch-labelled body
Lot & expiry printed
USP Type I glass
Borosilicate, sealed
GLP3 RT vial
GLP3 RT
10 mg
DUBAI PEPTIDES
RESEARCH USE ONLY
BLACK RESEARCH SERIES

Research Applications

Where researchers apply it.

01 Obesity and Weight Management
Preclinical models demonstrate that this markedly reduces body weight through decreased food intake, delayed gastric emptying, and increased energy expenditure. Studies show superior efficacy compared to dual agonists, with substantial fat mass loss and preservation of lean mass in various obesity models.
02 Glycemic Control and Type 2 Diabetes
Enhances glucose-dependent insulin secretion, improves insulin sensitivity, and lowers fasting glucose and HbA1c levels in diabetic and prediabetic models. Its triple agonism supports better metabolic outcomes than single or dual incretin therapies.
03 Liver Health and MASLD/MASH
Investigations reveal potent reductions in liver fat content, improvements in steatosis, and modulation of fibrosis markers. Preclinical and early clinical data highlight its role in reversing metabolic dysfunction-associated steatotic liver disease through combined effects on lipid metabolism and inflammation.
04 Lipid Metabolism and Cardiovascular Support
Favorably alters lipid profiles by reducing triglycerides, LDL, and VLDL while promoting fat oxidation and ketone body production. Research explores its potential benefits in mitigating obesity-related cardiovascular risk factors.
05 Broader Metabolic and Oncologic Implications
Emerging studies suggest protective effects against obesity-associated cancer progression, with reduced tumor growth and immune reprogramming in preclinical tumor models, potentially linked to sustained weight loss and metabolic improvements.

— Verified & Documented

Every vial is backed by a Certificate of Analysis.

Each lot is independently characterised by HPLC and mass spectrometry, with identity, mass and purity documented per batch and available on request.

Additional quality-control testing, including sterility, endotoxin and heavy metals, is conducted periodically across our product range.

>99%
HPLC Purity
MS
Identity Confirmed
Certificate of Analysis
GLP3 RT · BATCH M6-2804 · QC RELEASE
PASS
IdentityConfirmed
Mass34.73 mg
Purity99.76%
AppearanceWhite Lyophilised
LabJanoshik Analytical (Independant)
Date15/06/26

Storage & Handling

Storage & Handling

Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.

Beyond Use Date

Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.