Omni Peptides
Ipamorelin
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↑ GH/IGF-1, better sleep & recovery, body recomposition
Ipamorelin is a synthetic pentapeptide and highly selective growth hormone secretagogue (GHS) that functions as a potent agonist of the ghrelin receptor (GHS-R1a). This research compound has attracted substantial scientific interest due to its ability to stimulate pulsatile endogenous growth hormone (GH) release from the anterior pituitary with minimal impact on other hormones such as prolactin, cortisol, or adrenocorticotropic hormone (ACTH). Preliminary and advanced preclinical studies indicate that Ipamorelin may promote lipolysis, support lean body mass, enhance recovery processes, and exhibit favorable pharmacokinetic properties including high selectivity and stability. Researchers utilize this peptide in laboratory and animal models to investigate mechanisms of GH axis modulation, body composition, tissue repair, and age-related endocrine changes. As a research-grade compound, Ipamorelin is intended exclusively for in vitro and animal studies. Scientists value its clean pharmacological profile, lack of significant appetite stimulation compared to other GHS compounds, and utility in advancing understanding of selective ghrelin receptor agonism in anabolic and metabolic research.
Research Applications
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Growth Hormone Secretion and PulsatilityPreclinical investigations demonstrate that Ipamorelin elicits robust, dose-dependent, and pulsatile GH release via specific activation of pituitary GHS-R1a receptors. Studies highlight its ability to mimic natural GH pulses while avoiding the broad hormonal perturbations seen with non-selective secretagogues.
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Body Composition and Anabolic EffectsResearch shows Ipamorelin promotes increases in lean muscle mass, improves nitrogen balance, and supports protein synthesis in various animal models. It has been explored for potential benefits in sarcopenia, cachexia, and recovery from catabolic states.
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Fat Metabolism and LipolysisIpamorelin enhances lipolytic activity and reduces fat accumulation in preclinical obesity and metabolic models, often in combination with other peptides. Investigations assess its role in improving body composition without inducing significant hyperglycemia or insulin resistance.
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Tissue Repair and RecoveryStudies indicate potential benefits in accelerating wound healing, tendon and cartilage repair, and bone metabolism through elevated GH/IGF-1 axis activity. Research explores its applications in models of injury, aging, and post-surgical recovery.
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Neuroprotection and Cognitive SupportEmerging preclinical data suggest neuroprotective properties, including possible modulation of brain-derived neurotrophic factor (BDNF) and improved outcomes in models of neurodegeneration, traumatic brain injury, and age-related cognitive decline.
Storage & Handling
Storage & Handling
Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.
Beyond Use Date
Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.