Omni Peptides
N-Acetyl Semax Amidate
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N-Acetyl Semax Amidate (also known as N-Acetyl Semax NH₂ or Ac-Semax Amidate) is a synthetic heptapeptide derived from Semax with two key stabilizing modifications: N-terminal acetylation and C-terminal amidation. These changes significantly improve enzymatic resistance (especially against aminopeptidases), enhance metabolic stability, and often improve blood-brain barrier penetration and duration of action compared to standard Semax.
This research compound retains the core ACTH(4-10) analog sequence (Met-Glu-His-Phe-Pro-Gly-Pro) and is studied for its potent nootropic, neuroprotective, neurotrophic, and cognitive-enhancing properties. Preclinical research suggests it strongly upregulates BDNF and TrkB expression, modulates dopaminergic and serotonergic systems, reduces oxidative stress and neuroinflammation, and supports neuroplasticity with potentially superior pharmacokinetics to unmodified Semax.
Research Applications
Storage & Handling
Storage & Handling
Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.
Beyond Use Date
Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.
— About this compound
N-Acetyl Semax Amidate is a synthetic nootropic heptapeptide analogue.
N-Acetyl Semax Amidate (also known as N-Acetyl Semax NH₂ or Ac-Semax Amidate) is a synthetic heptapeptide derived from Semax with two key stabilizing modifications: N-terminal acetylation and C-terminal amidation. These changes significantly improve enzymatic resistance (especially against aminopeptidases), enhance metabolic stability, and often improve blood-brain barrier penetration and duration of action compared to standard Semax.
This research compound retains the core ACTH(4-10) analog sequence (Met-Glu-His-Phe-Pro-Gly-Pro) and is studied for its potent nootropic, neuroprotective, neurotrophic, and cognitive-enhancing properties. Preclinical research suggests it strongly upregulates BDNF and TrkB expression, modulates dopaminergic and serotonergic systems, reduces oxidative stress and neuroinflammation, and supports neuroplasticity with potentially superior pharmacokinetics to unmodified Semax.
Research Applications
Where researchers apply it.
— Verified & Documented
Every vial is backed by a Certificate of Analysis.
Each lot is independently characterised by HPLC and mass spectrometry, with identity, mass and purity documented per batch and available on request.
Additional quality-control testing, including sterility, endotoxin and heavy metals, is conducted periodically across our product range.
Storage & Handling
Storage & Handling
Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.
Beyond Use Date
Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.