Omni Peptides
GHK-Cu Copper Peptide
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Collagen stimulation, wound repair, hair & skin benefits
GHK-Cu is a synthetic copper-bound tripeptide that mimics the naturally occurring glycyl-L-histidyl-L-lysine (GHK) sequence complexed with copper(II) ions, a motif identified in human plasma and extracellular matrix proteins. This research compound has attracted extensive scientific scrutiny for its multifaceted roles in tissue remodeling, wound healing, and regenerative processes. Preliminary investigations reveal that GHK-Cu may stimulate extracellular matrix synthesis, enhance antioxidant defenses, and modulate inflammatory pathways. Researchers employ this peptide in laboratory settings to probe mechanisms of dermal repair, fibrosis modulation, and angiogenesis, particularly in models of cutaneous injury, aging skin, and systemic tissue damage. As a research-grade compound, GHK-Cu is intended exclusively for in vitro and animal studies. Scientists appreciate its utility in elucidating copper-mediated peptide signaling in regenerative biology.
Research Applications
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Dermal Regeneration and Anti-AgingPreclinical and ex vivo studies show that GHK-Cu robustly stimulates collagen, elastin, and glycosaminoglycan production while promoting fibroblast proliferation and matrix remodeling. It has been observed to improve skin density, elasticity, and reduce wrinkle parameters in photoaged models.
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Wound Healing and Tissue RepairGHK-Cu accelerates epithelialization, granulation tissue formation, and wound contraction in various animal models, including ischemic, diabetic, and burn injuries. Research demonstrates enhanced closure rates and improved biomechanical properties of healed tissues.
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Angiogenesis and Vascular SupportGHK-Cu upregulates VEGF and bFGF expression, facilitating new blood vessel formation and improving nutrient delivery to hypoxic or damaged sites.
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Antioxidant and Anti-Inflammatory EffectsIt elevates superoxide dismutase activity, scavenges reactive oxygen species, and suppresses pro-inflammatory cytokines such as TNF-α and IL-6, fostering a pro-regenerative microenvironment.
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Broader Systemic ProtectionInvestigations suggest potential in reducing fibrosis, supporting nerve regeneration, and mitigating oxidative damage in pulmonary and cardiovascular models.
Storage & Handling
Storage & Handling
Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.
Beyond Use Date
Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.