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Omni Peptides

TB-500 (TB4)

Regular price Dhs. 450.00 AED
Regular price Sale price Dhs. 450.00 AED
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Accelerates wound/tendon/ligament healing, anti-inflammatory

TB-500 (also known as Thymosin Beta-4 or TB-4) is a synthetic peptide that replicates the active sequence of thymosin beta-4, a naturally occurring protein involved in actin sequestration and cellular motility. This research compound has attracted substantial scientific attention for its potential roles in wound healing and tissue regeneration studies. Preliminary investigations indicate that TB-500 may facilitate cell migration, support angiogenic processes, and modulate inflammatory responses. Researchers employ this peptide in laboratory environments to explore mechanisms of tissue repair, particularly in models of dermal, corneal, cardiac, and musculoskeletal injuries. As a research-grade compound, TB-500 is designated solely for in vitro and animal studies. Scientists appreciate its capacity to enhance knowledge of actin-regulated regenerative pathways.

Molecular Formula
C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular Weight
4963.5 g/mol
Sequence
Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
  • Musculoskeletal and Soft Tissue Regeneration
    Preclinical studies demonstrate that TB-500 markedly accelerates the healing of muscles, tendons, ligaments, and skin wounds. It enhances cell migration and actin dynamics, improving tissue remodeling and flexibility in injury models.
  • Wound Healing and Dermal Repair
    TB-500 promotes re-epithelialization and collagen deposition in cutaneous wounds. Research has examined its potential in accelerating closure of chronic ulcers, pressure sores, and corneal injuries while minimizing scar formation.
  • Angiogenesis and Vascular Support
    TB-500 stimulates the formation of new blood vessels through upregulation of pathways involving VEGF and endothelial cell differentiation. This process is essential for nutrient delivery and oxygenation in ischemic or damaged tissues.
  • Cardiovascular and Neuroprotective Effects
    Investigations reveal its contributions to cardiac repair post-injury and protection of neural tissues. Studies suggest potential benefits in myocardial recovery and reduction of oxidative stress in brain models.
  • Anti-Inflammatory Properties
    It suppresses pro-inflammatory mediators, downregulates cytokines, and promotes resolution of inflammation, shifting toward pro-regenerative cellular environments.
Storage & Handling

Lyophilised vials are stable at −20°C for up to 2 years unopened. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.

Beyond Use Date

Pre-filled formats (cartridge, pen, nasal) carry a beyond-use date of typically 4–8 weeks from receipt. ≥98% purity by HPLC. For in vitro and preclinical research use only — not for human or veterinary use.